Actos Bladder Cancer
Actos ®, manufactured by Japanese company Takeda Pharmaceutical Company, Ltd., has been prescribed for many patients with type 2 diabetes. Studies show that prolonged use may increase the risk of developing bladder cancer, or cause or worsen conditions leading to congestive heart failure.
The manufacturers of all products, including prescription drugs, owe a duty to the consuming public to produce safe products, and to warn the public of any known health risks associated with the use of their product. If a manufacturer or seller of a dangerous product violates this duty, and the violation results in harm, the manufacturer may be held liable in a product liability lawsuit for selling a dangerous or defective product, or for negligence.
If you or someone close to you has been prescribed Actos® and has developed bladder cancer, any other type of cancer, or heart problems after taking Actos®, contact the North Carolina personal injury attorneys at Grimes Teich Anderson LLP to discuss your options.Why is Actos ® Prescribed for Diabetics?
Actos® is the marketing name for pioglitazone hydrochloride (pioglitazone), which is taken orally in tablet form by patients with type 2 diabetes.
With diabetes, the pancreas does not produce enough insulin (or the cells do not properly respond to insulin) to enable the cells to utilize glucose, which comes from digested sugars and starch. This causes glucose build up in the blood and, over time, this can lead to kidney, nerve, and heart damage, as well as blindness.
Pioglitazone functions by helping the body respond properly to insulin. Pioglitazone works in conjunction with diet, regular exercise, and taking additional anti-diabetic medications (e.g., metformin, which suppresses glucose formation in the liver, or sulfanyluria drugs, which increase insulin release by the pancreas).If You Take Actos®, Be Aware of the Risk for Bladder Cancer and Congestive Heart Failure
Nearly 26 million Americans are diabetic. Not surprisingly, then, in 2010, Actos® was the ninth best selling drug in the United States, with revenues exceeding $3.5 billion, according to a report in Pharmacy Times.
However, the FDA recently issued several alerts for pioglitazone based upon epidemiological studies indicating that prolonged use may be associated with an increased risk of bladder cancer. Although the FDA has not recalled the drug, it has required additional warnings. Further, Actos® is now banned in France, and is no longer prescribed in Germany.
While diabetics already experience specific types of increased health risks, patients who experience adverse reactions to Actos® should be alert for warning signs. Patients should contact their doctor at once if they experience classic symptoms of heart problems, such as shortness of breath, swelling, rapid weight gain, or other symptoms. Early symptoms of bladder cancer can include sudden urges to urinate, frequent urination in small amounts, blood or blood clots in the urine, painful urination, and weight loss.
At particular risk of responding adversely to Actos® are diabetic patients who exhibit known risk factors, such as:
- A history of bladder cancer
- Heart problems
- Congestive heart failure
- Liver disease
- An allergy to pioglitazone
If you or a close relative has developed bladder or any other type of cancer, heart problems, or other serious adverse effects after using Actos®, you may be entitled to a legal remedy in a product liability lawsuit. The North Carolina product liability lawyers at Grimes Teich Anderson LLP have assisted numerous victims injured by defective medical devices and drugs to recover damages from the companies responsible. Available damages may include compensation for:
- Pain and suffering
- Temporary or permanent physical impairment
- Medical costs and treatment
- Loss of earnings
- Loss of income
Further, if the injury results in death, surviving family members may be able to recover compensation in a wrongful death lawsuit.
Grimes Teich Anderson LLP has offices in Asheville, Rutherfordton, Waynesville, Franklin and Spruce Pine, North Carolina, as well as in Greenville and Gaffney, South Carolina. If you would like a no-cost, no-obligation consultation on whether you may have a claim due to an adverse reaction to Actos®, contact us toll-free at (800) 533-6845, or complete our confidential case evaluation form on this website.